Research so far seems to have found that 1:1 CBD:THC ratio provides the most therapeutic relief across wide categories of ailments, with just minor side effects. This proportion between cannabinoids is having the best effect on sleep, pain and muscle spasms reduction, and it is under research for the treatment of autism, cancer, fibromyalgia, and skin diseases. The relaxation comes with very light high effect and little euphoria. Discreet, convenient and reliable. Apply to any venous area of the skin for best results Provides 8-12 hours of unsurpassed, systemic relief. High bioavailability, 15-30-minute uptake time.