Harlequin is a 75/25 sativa-dominant strain renowned for its reliable expression of CBD. A descendant of Colombian Gold, a Nepali indica, and Thai and Swiss landrace strains, you can depend on Harlequin to provide clear-headed, alert sativa effects. Unlike most high-CBD strains, Harlequin almost always develops a CBD:THC ratio of 5:2, making this strain one of the most effective out there for treatment of pain and anxiety, as CBD can counteract THC’s paranoia while amplifying its painkilling properties.